SPINA (structure parameter inference approach) is a method for calculating constant structure parameters of endocrine feedback control systems in vivo from hormone levels obtained from serum or plasma.
A first successful implementation applies to evaluation of thyroid function. It allows for calculating the thyroid's maximum secretory capacity (GT or SPINA-GT) and the sum activity of peripheral 5'-deiodinases (GD or SPINA-GD) from levels of TSH, (F)T4 and (F)T3 that have been determined once only (SPINA Thyr).
SimThyr is a simulation program for thyroid homeostasis. It is based on a published nonlinear parametric isomorphic model of thyrotropic feedback control. Applications of SimThyr cover generation of hypotheses for biomedical research, education and presentation. Binaries and sourcecode are available for Mac OS, Mac OS X, Windows, Linux and other Unix derivatives.
The PUMA Repository (Pascal units for medical applications) is a collection of reusable source code for bioinformatics. It is compatible with Lazarus and Free Pascal, parts of the source code can also be used with Delphi and winsoft Pocket Studio.
Components of the PUMA repository include a unit converter for transforming instrumentation readouts consisting of a numerical value and a measurement unit, and an HL7 engine for reading, parsing, compiling and writing HL7 messages.
Spectroscopic Image Visualization and Computing (SIVIC) is an open-source, standards-based software framework and application suite for processing and visualization of DICOM MR Spectroscopy data. Through the use of DICOM, SIVIC aims to facilitate the application of MRS in medical imaging studies.
DataPall is a free software system specifically designed to assist palliative care providers in record keeping, data management, and reporting. It is especially tailored to programs in low-resource settings. Rice 360 interns in Malawi developed DataPall, an electronic medical records system tailored to the needs of palliative care providers in the region. DataPall offers a user-friendly interface that allows health workers to accurately and efficiently input appointment records. The program allows for individual patient tracking and aggregate data management.
MeVisLab represents a platform for image processing research and development with a focus on medical imaging. It allows fast integration and testing of new algorithms and the development of application prototypes that can be used in clinical environments.
SCIRun is a problem solving environment or "computational workbench" in which a user selects software modules that can be connected in a visual programing environment to create a high level workﬂow for experimentation. Each module exposes all the available parameters necessary for scientists to adjust the outcome of their simulation or visualization. The networks in SCIRun are flexible enough to enable duplication of networks and creation of new modules.
Apache clinical Text Analysis and Knowledge Extraction System (cTAKES) is an open-source natural language processing system for information extraction from electronic medical record clinical free-text. It processes clinical notes, identifying types of clinical named entities from various dictionaries including the Unified Medical Language System (UMLS) - medications, diseases/disorders, signs/symptoms, anatomical sites and procedures.