%0 Journal Article %J J Am Med Inform Assoc %D 2015 %T Virtualization of Open-Source Secure Web Services to Support Data Exchange in a Pediatric Critical Care Research Network. %A Frey, Lewis J %A Sward, Katherine A %A Newth, Christopher Jl %A Khemani, Robinder G %A Cryer, Martin E %A Thelen, Julie L %A Enriquez, Rene %A Shaoyu, Su %A Pollack, Murray M %A Harrison, Rick E %A Meert, Kathleen L %A Berg, Robert A %A Wessel, David L %A Shanley, Thomas P %A Dalton, Heidi %A Carcillo, Joseph %A Jenkins, Tammara L %A Dean, J Michael %X

OBJECTIVES: To examine the feasibility of deploying a virtual web service for sharing data within a research network, and to evaluate the impact on data consistency and quality.

MATERIAL AND METHODS: Virtual machines (VMs) encapsulated an open-source, semantically and syntactically interoperable secure web service infrastructure along with a shadow database. The VMs were deployed to 8 Collaborative Pediatric Critical Care Research Network Clinical Centers.

RESULTS: Virtual web services could be deployed in hours. The interoperability of the web services reduced format misalignment from 56% to 1% and demonstrated that 99% of the data consistently transferred using the data dictionary and 1% needed human curation.

CONCLUSIONS: Use of virtualized open-source secure web service technology could enable direct electronic abstraction of data from hospital databases for research purposes.

%B J Am Med Inform Assoc %8 2015 Mar 21 %G eng %R 10.1093/jamia/ocv009