|Title||JULIDE: a software tool for 3D reconstruction and statistical analysis of autoradiographic mouse brain sections.|
|Publication Type||Journal Article|
|Year of Publication||2010|
|Authors||Ribes, D, Parafita, J, Charrier, R, Magara, F, Magistretti, PJ, Thiran, J-P|
|Keywords||Animals, Autoradiography, Brain, Carbon Radioisotopes, Deoxyglucose, Image Processing, Computer-Assisted, Imaging, Three-Dimensional, Male, Maze Learning, Mice, Mice, Inbred C57BL, Reproducibility of Results, Software|
In this article we introduce JULIDE, a software toolkit developed to perform the 3D reconstruction, intensity normalization, volume standardization by 3D image registration and voxel-wise statistical analysis of autoradiographs of mouse brain sections. This software tool has been developed in the open-source ITK software framework and is freely available under a GPL license. The article presents the complete image processing chain from raw data acquisition to 3D statistical group analysis. Results of the group comparison in the context of a study on spatial learning are shown as an illustration of the data that can be obtained with this tool.
|Alternate Journal||PLoS ONE|
|PubMed Central ID||PMC2991313|
Please note that this Website is not maintained any longer and contains probably outdated information. You are still welcome to use it if it is of any help.