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SPINA Thyr

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SPINA (structure parameter inference approach) is a method for calculating constant structure parameters of endocrine feedback control systems in vivo from hormone levels obtained from serum or plasma.

A first successful implementation applies to evaluation of thyroid function. It allows for calculating the thyroid's maximum secretory capacity (GT or SPINA-GT) and the sum activity of peripheral 5'-deiodinases (GD or SPINA-GD) from levels of TSH, (F)T4 and (F)T3 that have been determined once only (SPINA Thyr).

SimThyr

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SimThyr is a simulation program for thyroid homeostasis. It is based on a published nonlinear parametric isomorphic model of thyrotropic feedback control. Applications of SimThyr cover generation of hypotheses for biomedical research, education and presentation. Binaries and sourcecode are available for Mac OS, Mac OS X, Windows, Linux and other Unix derivatives.

PUMA repository

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The PUMA Repository (Pascal units for medical applications) is a collection of reusable source code for bioinformatics. It is compatible with Lazarus and Free Pascal, parts of the source code can also be used with Delphi and winsoft Pocket Studio.
Components of the PUMA repository include a unit converter for transforming instrumentation readouts consisting of a numerical value and a measurement unit, and an HL7 engine for reading, parsing, compiling and writing HL7 messages.

tranSMART

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tranSMART is a knowledge management platform that enables scientists to develop and refine research hypotheses by investigating correlations between genetic and phenotypic data, and assessing their analytical results in the context of published literature and other work.

The integration, normalization, and alignment of data in tranSMART permits users to explore data very efficiently to formulate new research strategies. Some of tranSMART's specific applications include:

openEHR Ruby

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This is a stable release of Ruby openEHR implementation project. This release is based on openEHR specification release 1.0.2. We implemented almost of the specifications of the openEHR. The work is still in progress to implement related tools, such as archetype validator or serializer. Formerly, we named this package as open_ehr, but changed to openehr from release 1.1.0. 1.0.x versions are obsoleted. The intention is to have a sample EHR to utilize all over the world quickly with Ruby on Rails for many other porject.

This package includes:

ADL 1.4 parser

OpenInfoButton

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In the last 20 years, researchers have investigated solutions to enable seamless access to online resources within the context of electronic health record (EHR) systems. “Infobuttons” are among these solutions. Based on contextual attributes that describe the EHR user, the patient, and the care setting, infobuttons anticipate clinicians’ information needs and provide automated links to a set of relevant knowledge resources to assist clinical decision support.

Open PHACTS

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What is Open PHACTS?
To reduce the barriers to drug discovery in industry, academia and for small businesses, the Open PHACTS consortium is building the Open PHACTS Discovery Platform. This will be freely available, integrating pharmacological data from a variety of information resources and providing tools and services to question this integrated data to support pharmacological research.
The project is ending in August 2014.

MRIdb: Medical imaging database

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MRIdb is an end-to-end data management system for MRI, combining the DCM4CHEE DICOM server with a bespoke front-end packaged into an easily deployable virtual machine. It interfaces directly with MRI scanners and handles image storage, retrieval and export. It provides role-based access control, patient-study assignment, and extensive auditing. MRIdb is the result of an ongoing collaboration between the BSS and the Imaging Sciences Department of Imperial College.

cTAKES

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Apache clinical Text Analysis and Knowledge Extraction System (cTAKES) is an open-source natural language processing system for information extraction from electronic medical record clinical free-text. It processes clinical notes, identifying types of clinical named entities from various dictionaries including the Unified Medical Language System (UMLS) - medications, diseases/disorders, signs/symptoms, anatomical sites and procedures.

Raxa JSS EMR

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The Raxa JSS EMR is an information management system ("Raxa") designed for and to be initially implemented at the Jan Swasthya Sahyog (JSS), a healthcare non-governmental organization (NGO) working in a largely rural, underserved community in India. Raxa JSS EMR is an OpenMRS based Health Information System.

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