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OnkoDICOM

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OnkoDICOM was created with Radiation Oncologists to allow Radiation Oncologists to do research on DICOM standard image sets (DICOM-RT, CT, MRI, PET) using open source technologies, such as pydicom, dicompyler-core, PySide6, PIL, and matplotlib. OnkoDICOM is cross platform, open source software, and welcomes contributions from the wider community via GitHub .

AETHER

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Aether is a platform. It’s not tool that can just be deployed and used out of the box (but if that’s what you’re looking for, you might want to look at Gather). Instead it’s a set of modules and best practices for the real-time manipulation and publication of data to a destination of your choice.
Aether is for you if:
you already have a large amount of data, but it’s in a format that makes it unwieldy or hard to use
you have a data source and a data location, but you just can’t get them to speak the same language

SPARK

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Spark is a public domain FHIR server developed in C#, initially built by Firely and as of recently being maintained by Kufu.
Spark implements a major part of the FHIR specification and has been used and tested during several HL7 WGM Connectathons.

The Spatiotemporal Epidemiological Modeler (STEM) Project

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The Spatiotemporal Epidemiological Modeler (STEM) tool is designed to help scientists and public health officials create and use spatial and temporal models of emerging infectious diseases. These models can aid in understanding and potentially preventing the spread of such diseases.

i2b2

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i2b2 (Informatics for Integrating Biology and the Bedside) is an NIH-funded National Center for Biomedical Computing based at Partners HealthCare System. The i2b2 Center is developing a scalable informatics framework that will enable clinical researchers to use existing clinical data for discovery research and, when combined with IRB-approved genomic data, facilitate the design of targeted therapies for individual patients with diseases having genetic origins. This platform currently enjoys wide international adoption by the CTSA network, academic health centers, and industry.

IDRT - Integrated Data Repository Toolkit

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i2b2 has turned out to be a very valuable component for secondary use of routine clinical data. Its pragmatic database schema allows merging of data from heterogeneous data sources, and the intuitive user interface enables easy querying and powerful processing. However, it's a component rather than a complete solution: The user is facing several barriers when integrating i2b2 into the operational workflow.

Ogles2

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Ogles2 is an interactive slice and volume visualization and analysis tool based on Open Inventor / Coin3D. Ogles2 allows for reproducing the workflow of frame based stereotactic neurosurgery. In the long run it strives for being an open source stereotactic planning and analysis system. Ogles2 is NOT APPROVED FOR CLINICAL USE.

DeVIDE

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DeVIDE, or the Delft Visualisation and Image processing Development Environment, is a cross-platform software framework for the rapid prototyping, testing and deployment of visualisation and image processing algorithms. The software was developed within the Visualisation group. DeVIDE's primary (and currently only) front-end is a data-flow boxes-and-lines network editor. In this regard, it is very similar to AVS, OpenDX, Khoros or VISSION. DeVIDE integrates functionality from libraries such as VTK, ITK, GDCM, DCMTK, numpy and matplotlib. It is being very actively developed.

SIVIC

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Spectroscopic Image Visualization and Computing (SIVIC) is an open-source, standards-based software framework and application suite for processing and visualization of DICOM MR Spectroscopy data. Through the use of DICOM, SIVIC aims to facilitate the application of MRS in medical imaging studies.

SCIRun

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SCIRun is a problem solving environment or "computational workbench" in which a user selects software modules that can be connected in a visual programing environment to create a high level workflow for experimentation. Each module exposes all the available parameters necessary for scientists to adjust the outcome of their simulation or visualization. The networks in SCIRun are flexible enough to enable duplication of networks and creation of new modules.

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